x| 1. forduló | 1 | X | 2 | ||||||||||
| 2021.09.19. 15:00 | info | Vége | Virtus Matino | 1 - 1 | FC San | (0 - 0) | 0.00 | 0.00 | 0.00 | H2H | |||
| 2021.09.19. 15:00 | info | Vége | ACD Nardo | 4 - 2 | Team Altamura | (3 - 1) | 2.45 | 3.35 | 2.88 | odds | H2H | ||
| 2021.09.19. 15:00 | info | Vége | Mariglianese | 0 - 2 | Sorrento | (0 - 2) | 0.00 | 0.00 | 0.00 | H2H | |||
| 2021.09.19. 15:00 | info | Vége | Gravina | 1 - 2 | Casarano | (0 - 1) | 3.25 | 3.20 | 2.18 | odds | H2H | ||
| 2021.09.19. 15:00 | info | Vége | Lavello | 1 - 1 | Madrepietra Daunia | (1 - 0) | 1.72 | 3.72 | 4.84 | odds | H2H | ||
| 2021.09.19. 15:00 | info | Vége | Francavilla | 2 - 1 | Brindisi | (1 - 0) | 2.30 | 3.20 | 3.24 | odds | H2H | ||
| 2021.09.19. 15:00 | info | Vége | Casertana | 2 - 1 | Nola | (0 - 1) | 0.00 | 0.00 | 0.00 | H2H | |||
| 2021.09.19. 15:00 | info | Vége | Bitonto | 2 - 2 | Rotonda | (2 - 0) | 2.00 | 3.38 | 3.52 | odds | H2H | ||
| 2021.09.19. 15:00 | info | Vége | Bisceglie | 0 - 0 | Nocerina | (0 - 0) | 2.27 | 3.07 | 2.95 | odds | H2H | ||
| 2021.09.19. 15:00 | info | Vége | Audace Cerignola | 3 - 1 | Citta di | (2 - 1) | 1.72 | 3.70 | 4.63 | odds | H2H | ||